As noted above, in men, most studies show that bringing low testosterone up to the normal level is very healthy. Testosterone decreases angina and leg artery blockages, improves cholesterol, and helps improve insulin function in diabetics. In a small percent of men, problems with slowing urination and a worsening of male pattern baldness is seen. If this occurs, these side effects can usually be blocked by taking the herb saw Palmetto (160 mg twice daily) along with the testosterone. Fortunately, both of these problems have been fairly uncommon.
Fluid and electrolyte disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (see WARNINGS ).
Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
Nervous system: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions.
Vascular Disorders: venous thromboembolism
Miscellaneous: Inflammation and pain at the site of intramuscular injection.