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I am a two-time survior of the devasting bacterial infection known as C-Diff. Since I am an otherwise completely healthy female (was 35 and 44 when I contracted), it was unexpected that the disease would nearly kill me – twice. I have taken liquid vancomycin for nearly nine months now, but it has not cured me. I had the good fortune of learning from my infectious disease doctor and obtaining an opinion from an expert at Johns Hopkins Hospital about my case, and both concurred that I should consider opting for a fecal transplant as vancomycin hasn’t cured me. Although the procedure is usually done at the hospital and is 90-95% effective (so I am told), my husband and I are doing the home-style version. A fecal transplant is done by taking the stole of a healthy, close family member, mixing it with saline solution in a blender, putting it through a seive, and “inplanting” the donor’s good bacteria via an enema bottle into your intestines via your rectum. Although it was quite disgusting the first day, it gets easier. I noticed a dramatic improvement within 12 hours. Anyone having gone through a severe case of C-Diff knows that the fecal transplant procedure is not nearly as tramatic and painful as living with this infection. Quite frankly, the fecal transplant may save my life.
Although no teratogenicity was observed in animal reproduction studies, delayed fetal ossification was observed when sertraline was administered during the period of organogenesis at doses less than the maximum recommended human dose (MRHD) in rats and doses times the MRHD in rabbits on a mg/m 2 basis in adolescents. When sertraline was administered to female rats during the last third of gestation, there was an increase in the number of stillborn pups and pup deaths during the first four days after birth at the MRHD [ See Data ].