Im not saying at all that it has to be run for a minimum of 16 weeks or that 600 is the minimum I'm just speaking from my own 100% strictly based on my results with drug and from the man who taught me about most of my gear use (very well known but I won't say a name). I tried running Eq at lower doses and saw absolutely NOTHING from it from multiple dealers both domestic and overseas. 600mg is where I finally start to see some noticeable gains from it mostly in recovery/increased stamina. Once I pushed it to 900 I saw those traits magnified greatly, along with a massive increase in appetite, and from a strictly vain aspect this is when the absolute gross gross and spider web veins appeared for me. As for the 16 weeks time frame once again for me the longer i ran it better the gains were. I have ran it for up to 24 weeks at varying doses from 600-1200mg a week.