If the person has anemia due to illness such as stomach ulcers, it is important that the ulcer is treated medically first. In the case of colon cancer, surgery is done to remove cancer and this causes excessive blood loss and anemia. In persons with bone marrow damage or those that have undergone chemotherapy or in those with kidney failure, epogen and procrit is administered to stimulate red blood cell production. In some cases, medication causes low HCT and one needs to consult the doctor in order to get alternative medication for the same.
The authors compared the efficacy of caffeine, methylphenidate, and d-amphetamine in children with minimal brain dysfunction using a double-blind crossover design. The slight improvement with caffeine was not significantly better than placebo. Both prescription drugs resulted in significant improvement and were significantly superior to caffeine. The authors suggest that the discrepancy between these results and an earlier, more optimistic report may stem from the use in this study of pure caffeine rather than whole coffee. [Editor's note: At the time of some of these earlier studies, the terms "Attention Deficit Disorder (ADD)" or "Attention-Deficit/Hyperactivity Disorder (ADHD)" had not been included in the DSM. The term "Minimal Brain Dysfunction" was one of the diagnostic distinctions that we have now come to describe as ADD (DSM-III) or one of the forms of ADHD (DSM-IV)] .